Dentists believe that their profession is more stressful than other health professions. They are prone to professional stress, burnout, anxiety disorders and clinical depression, owing to the nature of clinical practice and the personality traits common among those who decide to pursue careers in dentistry. The most stressful stressors were financial issues. Stress can cause many health problems such as of cardiovascular disease, musculoskeletal, brain injury, emotional illness, ulcers, colitis, hypertension, asthma lower back pain, eye strain, alcoholism, drug addiction, mental depression and suicide. Also, it influences on family relations, teamwork and patients. It is important for dentists to recognize the symptoms and the effects of stress on physical, psychological and professional well being. Managing of stress can not cure it totally, but it can minimize it gradually. Stress management depends on understanding its causes and try to find the ways to avoid them. To enjoy satisfying professional and personal lives, dentists must be aware of the importance of maintaining good physical and mental health. Managing of stress depends on adopting the preventive measures from the early stages of stress. It includes the changing of work environment, building good relations with patients and teamwork, family members, and friends. Also practicing the sport, having rest and relaxing times, creating social relations with workers and continuing education.